Changes to AutoDiscover settings in Exchange are cached by each AutoD IIS application for approximately 2 hours. If you want to have configuration changes available quickly, it is required to restart the AutoD application pool on each Client Access Server serving AutoD request. Additionally, you have to restart the MSExchangeServiceHost process as well.
The PowerShell code can restart the application pool and the MSExchangeServerHost process across all Exchange 2013 servers.
Restart Application Pool
Get-ExchangeServer | ? { $_.AdminDisplayVersion -like '*15.*'} | % { Invoke-Command -ComputerName $_.Name -ScriptBlock {Restart-WebAppPool MSExchangeAutodiscoverAppPool } }
Restart MSExchangeServiceHost
Get-ExchangeServer | ? { $_.AdminDisplayVersion -like '*15.*'} | % { Invoke-Command -ComputerName $_.Name -ScriptBlock {Restart-Service MSExchangeServiceHost } }
Enjoy.
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